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POFUT1 抗体 (N-Term)

This anti-POFUT1 antibody is a 兔 多克隆 antibody detecting POFUT1 in WB, ELISA 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN6990964
发货至: 中国

Quick Overview for POFUT1 抗体 (N-Term) (ABIN6990964)

抗原

See all POFUT1 抗体
POFUT1 (Protein O-Fucosyltransferase 1 (POFUT1))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This POFUT1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 90-140, N-Term

    特异性

    At least two isoforms of POFUT1 are known to exist. This antibody is predicted to not cross-react with POFUT2.

    纯化方法

    POFUT1 Antibody is affinity chromatography purified via peptide column.

    免疫原

    POFUT1 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human POFUT1. The immunogen is located within amino acids 90 - 140 of POFUT1.

    亚型

    IgG
  • 应用备注

    POFUT1 antibody can be used for the detection of POFUT1 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    POFUT1 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    POFUT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    POFUT1 (Protein O-Fucosyltransferase 1 (POFUT1))

    别名

    POFUT1

    背景

    POFUT1 Antibody: POFUT1, an endoplasmic reticulum-residing member of the glycosyltransferase O-Fuc family, adds O-fucose through an O-glycosidic linkage to conserved serine or threonines in epidermal growth factor-like repeats of several cell surface and secreted proteins. Unlike its homolog POFUT2, POFUT1 can also catalyze the transfer of fucose to thrombospondin type 1 repeats. Many of the substrates of POFUT1 are involved in ligand-induced receptor signaling. One such protein is Notch, mouse ES cells lacking POFUT have normal levels of Notch receptors at the cell surface, but these receptors do not bind Notch ligands or exhibit Notch signaling.

    基因ID

    23509

    NCBI登录号

    NP_056167

    UniProt

    Q9H488

    途径

    Notch Signaling, SARS-CoV-2 Protein Interactome
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