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BST2 抗体 (N-Term)

This anti-BST2 antibody is a 兔 多克隆 antibody detecting BST2 in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN6990931
发货至: 中国

Quick Overview for BST2 抗体 (N-Term) (ABIN6990931)

抗原

See all BST2 抗体
BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))

适用

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人, 小鼠

宿主

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  • 1

克隆类型

  • 53
  • 17
多克隆

标记

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This BST2 antibody is un-conjugated

应用范围

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  • 1
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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 60-110, N-Term

    纯化方法

    Bst2 Antibody is affinity chromatography purified via peptide column.

    免疫原

    Bst2 antibody was raised against a 18 amino acid synthetic peptide near the amino terminus of the mouse Bst2. The immunogen is located within amino acids 60 - 110 of Bst2.

    亚型

    IgG
  • 应用备注

    Bst2 antibody can be used for detection of Bst2 by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Bst2 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    Bst2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))

    别名

    Bst2

    背景

    Bst2 Antibody: Bst2 was first identified as a novel terminal B-cell-restricted antigen termed HM1.24 that is expressed on certain bone marrow cells as well as other tissues. The surface expression of Bst2 on fibroblast cell lines facilitated the stromal cell-dependent growth of DW34, a pre-B-cell line, suggesting that this protein is involved in pre-B-cell growth. Later experiments also showed it to be upregulated in several myeloma cells. More recently, Bst2 was identified an inhibitor of retroviral release from human cells whose activity is antagonized by the HIV-1 accessory protein Vpu. While Bst2 caused retention of virions on cell surfaces or endocytosis into Bst2-positive compartments, its depletion abolished the viral requirement for Vpu for virus release. This activity may represent a potential therapeutic strategy for the treatment of HIV/AIDS.

    基因ID

    69550

    UniProt

    Q8R2Q8

    途径

    Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response
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