NPTX2 抗体 (AA 170-220)
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北京 101111
Quick Overview for NPTX2 抗体 (AA 170-220) (ABIN6990895)
抗原
See all NPTX2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 170-220
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纯化方法
- NPTX2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Anti-NPTX2 antibody was raised against a peptide corresponding to 16 amino acids near the center of human NPTX2. The immunogen is located within amino acids 170 - 220 of NPTX2.
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亚型
- IgG
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应用备注
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WB: 0.5-4 μ,g/mL, IHC: 5 μ,g/mL, IF: 20 μ,g/mL.
Antibody validated: Western Blot in human, mouse and rat samples, Immunohistochemistry in human and mouse samples, Immunofluorescence in human and mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- NPTX2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- NPTX2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- NPTX2 (Neuronal Pentraxin II (NPTX2))
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别名
- NPTX2
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背景
- NPTX2 Antibody: Neuronal pentraxin (NPTX) 2 was initially identified as a member of the pentraxin family having high homology to NPTX1. Unlike NPTX1 however, NPTX2 is expressed in testes, pancreas, liver, heart, skeletal muscle as well as brain. NPTX2 possesses the lectin properties common to the pentraxin family, promotes neurite outgrowth, and is rapidly regulated by neuronal activity. NPTX1 and NPTX2 form heterocomplexes that contribute to both activity-independent and -dependent excitatory synaptogenesis. Recently, NPTX2 has been found to be highly upregulated in Parkinsonian substantia nigra and localizes to Lewy bodies and Lewy neurites in sporadic Parkinson's disease (PD), suggesting that it is involved in the pathway dysregulation that underlies PD. This NPTX2 antibody is predicted to be specific to NPTX2 and not recognize NPTX1.
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分子量
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Predicted: 47kD
Observed: 47 kD kDa -
基因ID
- 4885
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NCBI登录号
- NP_002514
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UniProt
- P47972
抗原
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