UNC93B1 抗体 (N-Term)
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北京 101111
Quick Overview for UNC93B1 抗体 (N-Term) (ABIN6990887)
抗原
See all UNC93B1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 80-130, N-Term
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特异性
- Multiple isoforms of Unc93b are known to exist. This antibody will not cross-react with Unc93a.
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纯化方法
- Unc93b Antibody is affinity chromatography purified via peptide column.
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免疫原
- Unc93b antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human Unc93b. The immunogen is located within amino acids 80 - 130 of Unc93b.
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亚型
- IgG
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anti-Unc-93 Homolog B1 (UNC93B1) (AA 451-550) antibody
UNC93B1 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (AA 450-550) antibodyUNC93B1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (AA 83-135) antibodyUNC93B1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (AA 500-550) antibodyUNC93B1 适用: 人, 小鼠, 大鼠, 犬, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (AA 61-110) antibodyUNC93B1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 斑马鱼, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (N-Term) antibodyUNC93B1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (AA 300-597) antibodyUNC93B1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (N-Term) antibodyUNC93B1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Unc93b antibody can be used for the detection of Unc93b by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Unc93b Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Unc93b antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- UNC93B1 (Unc-93 Homolog B1 (UNC93B1))
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别名
- Unc93b
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背景
- Unc93b Antibody: The endoplasmic reticulum (ER) protein Unc93b, a human homolog of the C. elegans Unc93 gene, was initially identified by a forward genetic screen using N-ethyl-N-nitrosourea where a histidine-to-arginine substitution in Unc93b caused defects in Toll-like receptor (TLR) 3, 7 and 9 signaling. Unlike Unc93a, another homolog of the C. elegans Unc93 gene whose function is unknown, Unc93b specifically interacts with TLR3, 7 and 9, the histidine-to-arginine point mutation used to identify Unc93b abolishes this interaction. Mice carrying this point mutation are highly susceptible to infection with a number of viruses, indicating that Unc93b plays an important role in innate immunity.
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分子量
- 56, 66 kDa
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基因ID
- 81622
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UniProt
- Q9H1C4
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途径
- TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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