ATG12 抗体 (N-Term)
Quick Overview for ATG12 抗体 (N-Term) (ABIN6990837)
抗原
See all ATG12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- ATG12 Antibody is affinity chromatography purified via peptide column.
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免疫原
- ATG12 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human ATG12. The immunogen is located within the first 50 amino acids of ATG12.
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亚型
- IgG
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anti-Autophagy Related 12 (ATG12) (N-Term) antibody
ATG12 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 猴, 小鸡, 兔, Pig, Cat, 驴, 山羊, Hamster, 绵羊, Avian WB, IF 宿主: 山羊 Polyclonal unconjugated
anti-Autophagy Related 12 (ATG12) antibodyATG12 适用: 人 WB, ELISA, IHC, IF 宿主: 小鼠 Monoclonal 43CT73-3-5-5-4 unconjugated
anti-Autophagy Related 12 (ATG12) (AA 101-187) antibodyATG12 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Autophagy Related 12 (ATG12) (AA 1-74) antibodyATG12 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Autophagy Related 12 (ATG12) (AA 1-30), (N-Term) antibodyATG12 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7475 unconjugated
anti-Autophagy Related 12 (ATG12) (AA 1-50) antibodyATG12 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Autophagy Related 12 (ATG12) antibodyATG12 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Autophagy Related 12 (ATG12) (AA 79-128) antibodyATG12 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, 猴, 小鸡, 兔, Pig, Bat, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Autophagy Related 12 (ATG12) (AA 1-74) antibodyATG12 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H8 unconjugated
anti-Autophagy Related 12 (ATG12) (AA 1-140) antibodyATG12 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F9 unconjugated
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应用备注
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ATG12 antibody can be used for the detection of ATG10 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- ATG12 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- ATG12 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- ATG12 (Autophagy Related 12 (ATG12))
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别名
- ATG12
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背景
- ATG12 Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG12, another member of the autophagy protein family, forms a conjugate with ATG5, this conjugate has a ubiquitin-protein ligase (E3)-like activity for protein lipidation in autophagy. This conjugate also associates with innate immune response proteins such as RIG-I and VISA (also known as IPS-1), inhibiting type I interferon production and permitting viral replication in host cells. ATG12 has also been shown to interact with ATG10 in human embryonic kidney cells in the presence of ATG7. At least two isoforms of ATG12 are known to exist.
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基因ID
- 9140
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UniProt
- O94817
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途径
- Autophagy
抗原
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