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GSTP1 抗体 (AA 90-140)

This anti-GSTP1 antibody is a 兔 多克隆 antibody detecting GSTP1 in WB, ELISA, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6990833
发货至: 中国

Quick Overview for GSTP1 抗体 (AA 90-140) (ABIN6990833)

抗原

See all GSTP1 抗体
GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This GSTP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 90-140

    纯化方法

    GSTP1 Antibody is affinity chromatography purified via peptide column.

    免疫原

    GSTP1 antibody was raised against a 14 amino acid synthetic peptide from near the center of human GSTP1. The immunogen is located within amino acids 90 - 140 of GSTP1.

    亚型

    IgG
  • 应用备注

    GSTP1 antibody can be used for the detection of ATG10 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    GSTP1 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    GSTP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

    别名

    GSTP1

    背景

    GSTP1 Antibody: Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism (i.e., the metabolism of environmental mutagens and carcinogens) and may play a role in susceptibility to cancer. More recent experiments have suggested that differential expression of GSTP1 also contributes to the sensitivity of xenobiotics in the substantia nigra and may influence the pathogenesis of reactive oxygen species-induced neurological disorders such as Parkinson's disease. CpG island hypermethylation of the GSTP1 promoter leading to the silencing of the GSTP1 gene has also been linked to cancer.

    基因ID

    2950

    NCBI登录号

    NP_000843

    UniProt

    P09211

    途径

    Cellular Response to Molecule of Bacterial Origin
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