ZBP1 抗体 (C-Term)
Quick Overview for ZBP1 抗体 (C-Term) (ABIN6990827)
抗原
See all ZBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Multiple isoforms of ZBP1 are known to exist.
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纯化方法
- ZBP1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- ZBP1 antibody was raised against an 18 amino acid synthetic peptide from near the carboxy terminus of human ZBP1. The immunogen is located within the last 50 amino acids of ZBP1.
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亚型
- IgG
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anti-Z-DNA Binding Protein 1 (ZBP1) (AA 10-167) antibody
ZBP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Z-DNA Binding Protein 1 (ZBP1) (AA 2-100) antibodyZBP1 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 2C10 unconjugated
anti-Z-DNA Binding Protein 1 (ZBP1) (AA 1-411) antibodyZBP1 适用: 人, 小鼠 WB, IP, ICC 宿主: 小鼠 Monoclonal Zippy-1 unconjugated
anti-Z-DNA Binding Protein 1 (ZBP1) (AA 144-193) antibodyZBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Z-DNA Binding Protein 1 (ZBP1) (AA 1-200) antibodyZBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Z-DNA Binding Protein 1 (ZBP1) (C-Term) antibodyZBP1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ZBP1 antibody can be used for the detection of ZBP1 by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- ZBP1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- ZBP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- ZBP1 (Z-DNA Binding Protein 1 (ZBP1))
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别名
- ZBP1
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背景
- ZBP1 Antibody: Z-DNA binding protein 1 (ZBP1) belongs to a family of proteins that contain the Zalpha domain which binds specifically to left-handed Z-DNA and Z-RNA. ZBP1 was initially identified as a novel gene that was up-regulated in activated macrophages in mice bearing ascites tumors, suggesting that is may play a role in processes such as host response in neoplasia. More recent reports indicate that the cytosolic ZBP1 has can act like the toll-like receptor TLR9 by detecting cytosolic double-stranded (ds) DNA and trigger induction of type I interferon and other innate immune responses. It is thought that the binding of ZBP1 to dsDNA enhances its association with innate immune response proteins such as the IRF3 transcription factor and the serine/threonine kinase TBK1 (also known as NAK).
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分子量
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Predicted: 39, 45 kDa
Observed: 42 kDa -
基因ID
- 81030
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UniProt
- Q9H171
抗原
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