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ZBP1 抗体 (C-Term)

ZBP1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN783819
发货至: 中国
  • 抗原 See all ZBP1 抗体
    ZBP1 (Z-DNA Binding Protein 1 (ZBP1))
    抗原表位
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 25
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 21
    • 3
    • 1
    • 1
    克隆类型
    • 23
    • 3
    多克隆
    标记
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZBP1 antibody is un-conjugated
    应用范围
    • 23
    • 13
    • 13
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to ZBP1.
    纯化方法
    Affinity chromatography
    免疫原
    18 amino acid peptide from near the carboxy terminus of human ZBP1.
    Top Product
    Discover our top product ZBP1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    PBS containing 0.02 % sodium azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    ZBP1 (Z-DNA Binding Protein 1 (ZBP1))
    别名
    ZBP1 (ZBP1 产品)
    别名
    C20orf183 antibody, DAI antibody, DLM-1 antibody, DLM1 antibody, 2010010H03Rik antibody, Dai antibody, Dlm1 antibody, mZaDLM antibody, ZBP1 antibody, Z-DNA binding protein 1 antibody, ZBP1 antibody, Zbp1 antibody
    背景
    Z-DNA binding protein 1 (ZBP1) belongs to a family of proteins that contain the Za domain which binds specifically to left-handed Z-DNA and Z-RNA. ZBP1 was initially identified as a novel gene that was up-regulated in activated macrophages in mice bearing ascites tumors, suggesting that is may play a role in processes such as host response in neoplasia. More recent reports indicate that the cytosolic ZBP1 has can act like the toll-like receptor TLR9 by detecting cytosolic double-stranded (ds) DNA and trigger induction of type I interferon and other innate immune responses. It is thought that the binding of ZBP1 to dsDNA enhances its association with innate immune response proteins such as the IRF3 transcription factor and the serine/threonine kinase TBK1 (also known as NAK). Multiple isoforms of ZBP1 are known to exist.Synonyms: C20orf183, DLM1, Z-DNA-binding protein 1
    基因ID
    81030
    NCBI登录号
    NP_001153889
    UniProt
    Q9H171
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