DHX58 抗体 (AA 200-250)
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北京 101111
Quick Overview for DHX58 抗体 (AA 200-250) (ABIN6990807)
抗原
See all DHX58 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 200-250
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纯化方法
- LGP2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- LGP2 antibody was raised against a 11 amino acid synthetic peptide from near the center of human LGP2. The immunogen is located within amino acids 200 - 250 of LGP2.
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亚型
- IgG
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应用备注
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LGP2 antibody can be used for detection of LGP2 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- LGP2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- LGP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- DHX58 (DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58))
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别名
- LGP2
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背景
- LGP2 Antibody: Anti-viral innate immune responses are triggered by pathogen-associated molecular patters (such as the accumulation of intracellular nucleic acids resulting from virus infections) and represent the first line of defense against numerous infectious organisms. The Toll-like receptors (TLR) 3, 7, 8, and 9 are expressed in immune cells and function as transmembrane pattern recognition receptors to detect foreign nucleic acids. Other proteins that play similar roles, such as RIG-1 and MDA5 are members of a CARD-helicase family and are expressed in the cytoplasm. A third protein, LGP2, is similar to RIG-1 and MDA5, except for lacking a homologous CARD domain. It is thought to act as an element of negative-feedback regulation of intracellular antiviral signaling. At least four isoforms of LGP2 are known to exist.
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基因ID
- 79132
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UniProt
- Q96C10
抗原
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