PTK7 抗体 (C-Term)
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北京 101111
Quick Overview for PTK7 抗体 (C-Term) (ABIN6990782)
抗原
See all PTK7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 880-930, C-Term
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纯化方法
- PTK7 Antibody is affinity chromatography purified via peptide column.
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免疫原
- PTK7 antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human PTK7. The immunogen is located within amino acids 880 - 930 of PTK7.
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亚型
- IgG
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应用备注
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PTK7 antibody can be used for detection of PTK7 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human, mouse, and rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PTK7 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- PTK7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))
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别名
- PTK7
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背景
- PTK7 Antibody: Protein-tyrosine kinases (PTKs) play important roles in regulating cell proliferation and differentiation during development. One member of the PTK family, PTK7, has been suggested to regulate the planar cell polarity (PCP) pathway in vertebrates and may play a role in neural convergent extension and neural tube closure. PTK7 has also been implicated in the development of cancer. Loss of PTK7 expression was seen in several melanoma cell lines and biopsies. Conversely, high-throughput analysis of acute myeloid leukemia samples showed an increased level of PTK7 expression compared to normal bone marrow and purified CD34+ cells. Multiple isoforms of PTK7 are known to exist.
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基因ID
- 5754
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UniProt
- Q13308
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途径
- RTK signaling, Tube Formation
抗原
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