ORAI1 抗体 (C-Term)
Quick Overview for ORAI1 抗体 (C-Term) (ABIN6990774)
抗原
See all ORAI1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody is predicted to have no cross-reactivity to ORAI2 or ORAI3.
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纯化方法
- ORAI1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- ORAI1 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human ORAI1. The immunogen is located within the last 50 amino acids of ORAI1.
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亚型
- IgG
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anti-ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) (AA 200-212), (Extracellular) antibody
KO Validated ORAI1 适用: 小鼠 WB, IHC, FACS, IF, LCI, IC 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) (AA 1-87) antibodyORAI1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) (Internal Region) antibodyVerified ORAI1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) (C-Term) antibodyORAI1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) (AA 202-301) antibodyORAI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) (AA 145-173) antibodyORAI1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) (Extracellular) antibodyORAI1 适用: 人 WB, FACS, IF, LCI, IC 宿主: 小鼠 Monoclonal 3F11-D10-B9 unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) antibodyORAI1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) (AA 182-231) antibodyORAI1 适用: 人, Pig, 犬, 兔, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) (C-Term) antibodyORAI1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ORAI1 antibody can be used for detection of ORAI1 by Western blot at 0.5 - 2 μ,g/mL. ORAI1 often migrates at a higher than expected molecular weight in SDS-PAGE. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- ORAI1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- ORAI1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))
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别名
- ORAI1
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背景
- ORAI1 Antibody: Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI1 is a recently identified four-transmembrane spanning protein that is an essential component of CRAC. A missense mutation in this protein in humans is the cause of one form of hereditary severe combined immune deficiency (SCID) which results in ablated T-cell Ca++ entry. It has been suggested that ORAI1 functions as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor.
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基因ID
- 84876
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UniProt
- Q96D31
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途径
- TCR Signaling, BCR Signaling
抗原
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