MORF4 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for MORF4 抗体 (N-Term) (ABIN6990771)
抗原
See all MORF4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 20-70, N-Term
-
纯化方法
- MORF4 Antibody is affinity chromatography purified via peptide column.
-
免疫原
- MORF4 antibody was raised against a 18 amino acid synthetic peptide from near the amino terminus of human MORF4. The immunogen is located within amino acids 20 - 70 of MORF4.
-
亚型
- IgG
-
-
-
-
应用备注
-
MORF4 antibody can be used for the detection of MORF4 by Western blot at 1 and 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- MORF4 Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- MORF4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- MORF4 (Mortality Factor 4 (MORF4))
-
别名
- MORF4
-
背景
- MORF4 Antibody: Cellular senescence is the terminal non-dividing state that normal cells enter following completion of their proliferative potential. Fusions of immortal human cell lines with each other have led to their assignment to one of four complementation groups. Mortality factor 4 (MORF4) was identified as the lead member of a family of transcription factor-like proteins that reverses this immortal phenotype. Like other members in this family, MORF4 is localized to the nucleus and possesses transcription factor-like motifs such as helix-loop-helix and a leucine zipper motif that might allow it to form transcriptionally active homo- or heterodimers. MORF4 has been shown to bind to the transcription corepressors mSin3A and TLE, suggesting that together, these complexes may play a role in transcriptional repression of genes that lead to cellular senescence.
-
基因ID
- 10934
-
UniProt
- Q9Y690
抗原
-