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MORF4 抗体 (N-Term)

MORF4 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN783556
发货至: 中国
  • 抗原 See all MORF4 抗体
    MORF4 (Mortality Factor 4 (MORF4))
    抗原表位
    • 2
    • 2
    • 1
    • 1
    N-Term
    适用
    • 5
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 4
    • 1
    克隆类型
    • 3
    • 2
    多克隆
    标记
    • 5
    This MORF4 antibody is un-conjugated
    应用范围
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    18 amino acid peptide from near the amino terminus of human MORF4
    Top Product
    Discover our top product MORF4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • 抗原
    MORF4 (Mortality Factor 4 (MORF4))
    别名
    MORF4 (MORF4 产品)
    别名
    CSR antibody, CSRB antibody, SEN antibody, SEN1 antibody, mortality factor 4 (pseudogene) antibody, MORF4 antibody
    背景
    Cellular senescence is the terminal non-dividing state that normal cells enter following completion of their proliferative potential. Fusions of immortal human cell lines with each other have led to their assignment to one of four complementation groups. Mortality factor 4 (MORF4) was identified as the lead member of a family of transcription factor-like proteins that reverses this immortal phenotype. Like other members in this family, MORF4 is localized to the nucleus and possesses transcription factor-like motifs such as helix-loop-helix and a leucine zipper motif that might allow it to form transcriptionally active homo- or heterodimers. MORF4 has been shown to bind to the transcription corepressors mSin3A and TLE, suggesting that together, these complexes may play a role in transcriptional repression of genes that lead to cellular senescence.Synonyms: CSR, CSRB, SEN, SEN1, mortality factor 4
    UniProt
    Q9Y690
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