Stim2 抗体 (AA 140-190)
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北京 101111
Quick Overview for Stim2 抗体 (AA 140-190) (ABIN6990746)
抗原
See all Stim2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 140-190
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纯化方法
- STIM2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- STIM2 antibody was raised against a 17 amino acid synthetic peptide from near the center of human STIM2. The immunogen is located within amino acids 140 - 190 of STIM2.
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亚型
- IgG
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应用备注
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STIM2 antibody can be used for detection of STIM2 by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- STIM2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- STIM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Stim2 (Stromal Interaction Molecule 2 (Stim2))
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别名
- STIM2
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背景
- STIM2 Antibody: In T lymphocytes, the sole pathway for Ca++ entry following antigen-receptor binding is through store-operated Ca++-release-activated Ca++ (CRAC) channels. These channels are made up of the pore-forming subunit ORAI1 and the stromal interaction molecule 1 (STIM1), a protein that functions as a Ca++ sensor and activates the CRAC channels, migrating to the plasma membrane from endoplasmic reticulum (ER)-like sites which act as the Ca++ store. A related molecule, STIM2, acts to inhibit the STIM1-mediated store-operated Ca++ entry, and can form complexes with STIM1, suggesting they may play a coordinated role in controlling Ca++ entry. At least three isoforms of STIM2 are known to exist. This STIM2 antibody is predicted to have no cross-reactivity to STIM1.
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基因ID
- 57620
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NCBI登录号
- NP_065911
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UniProt
- Q9P246
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途径
- TCR Signaling, BCR Signaling
抗原
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