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Stim2 抗体 (C-Term)

This anti-Stim2 antibody is a 兔 多克隆 antibody detecting Stim2 in WB, ELISA, IHC (p) 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6990745
发货至: 中国

Quick Overview for Stim2 抗体 (C-Term) (ABIN6990745)

抗原

See all Stim2 抗体
Stim2 (Stromal Interaction Molecule 2 (Stim2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 34
多克隆

标记

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This Stim2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 抗原表位

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    C-Term

    纯化方法

    STIM2 Antibody is affinity chromatography purified via peptide column.

    免疫原

    STIM2 antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human STIM2. The immunogen is located within the last 50 amino acids of STIM2.

    亚型

    IgG
  • 应用备注

    STIM2 antibody can be used for detection of STIM2 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    STIM2 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    STIM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    Stim2 (Stromal Interaction Molecule 2 (Stim2))

    别名

    STIM2

    背景

    STIM2 Antibody: In T lymphocytes, the sole pathway for Ca++ entry following antigen-receptor binding is through store-operated Ca++-release-activated Ca++ (CRAC) channels. These channels are made up of the pore-forming subunit ORAI1 and the stromal interaction molecule 1 (STIM1), a protein that functions as a Ca++ sensor and activates the CRAC channels, migrating to the plasma membrane from endoplasmic reticulum (ER)-like sites which act as the Ca++ store. A related molecule, STIM2, acts to inhibit the STIM1-mediated store-operated Ca++ entry, and can form complexes with STIM1, suggesting they may play a coordinated role in controlling Ca++ entry. At least three isoforms of STIM2 are known to exist. This STIM2 antibody is predicted to have no cross-reactivity to STIM1.

    基因ID

    57620

    NCBI登录号

    NP_065911

    UniProt

    Q9P246

    途径

    TCR Signaling, BCR Signaling
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