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CD82 抗体 (C-Term)

This anti-CD82 antibody is a 兔 多克隆 antibody detecting CD82 in WB, ELISA, IHC (p) 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6990729
发货至: 中国

Quick Overview for CD82 抗体 (C-Term) (ABIN6990729)

抗原

See all CD82 抗体
CD82

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CD82 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 抗原表位

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    C-Term

    纯化方法

    KAI1 Antibody is affinity chromatography purified via peptide column.

    免疫原

    KAI1 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human KAI1. The immunogen is located within the last 50 amino acids of KAI1.

    亚型

    IgG
  • 应用备注

    KAI1 antibody can be used for detection of KAI1 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    KAI1 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    KAI1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    CD82

    别名

    KAI1

    背景

    KAI1 Antibody: KAI1 was initially identified from a T-cell activation study as a four-transmembrane protein that plays an accessory role in T-cell activation, and was later determined to act as a cancer metastasis suppressor gene. This protein is ubiquitously expressed at moderate to high levels in most tissues, but its expression is downregulated during tumor progression. The loss of KAI1 and p53 is associated with poor survival for prostate and other cancer patients. Recently, KAI1 was found to interact with DARC, the Duffy antigen for chemokines using a yeast two hybrid screen. It is thought that tumor cells dislodged from the primary tumor and expressing KAI1 interact with DARC proteins expressed on vascular cells, transmitting a senescent signal to the tumor cells, while tumor cells that have lost KAI1 expression can proliferate and potentially give rise to metastases. At least two isoforms of KAI1 are known to exist.

    基因ID

    3732

    NCBI登录号

    NP_002222

    UniProt

    P27701

    途径

    p53 Pathway
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