DARC 抗体 (N-Term)
Quick Overview for DARC 抗体 (N-Term) (ABIN6990728)
抗原
See all DARC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- DARC Antibody is affinity chromatography purified via peptide column.
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免疫原
- DARC antibody was raised against a 18 amino acid synthetic peptide from near the amino terminus of human DARC. The immunogen is located within the first 50 amino acids of DARC.
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亚型
- IgG
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anti-Duffy Blood Group, Chemokine Receptor (DARC) (N-Term) antibody
Verified DARC 适用: 人 WB, ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Duffy Blood Group, Chemokine Receptor (DARC) (AA 1-336) antibodyDARC 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Duffy Blood Group, Chemokine Receptor (DARC) (AA 71-330) antibodyDARC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Duffy Blood Group, Chemokine Receptor (DARC) (AA 1-63) antibodyDARC 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Duffy Blood Group, Chemokine Receptor (DARC) (AA 1-30), (N-Term) antibodyDARC 适用: 人 WB 宿主: 兔 Polyclonal RB42735 unconjugated
anti-Duffy Blood Group, Chemokine Receptor (DARC) antibodyDARC 适用: 人 ELISA, FACS, BP 宿主: 兔 Chimeric 2C3 unconjugated Recombinant Antibody
anti-Duffy Blood Group, Chemokine Receptor (DARC) (N-Term) antibody (Biotin)Verified DARC 适用: 人 WB, ELISA, IHC, FACS 宿主: 山羊 Polyclonal Biotin
anti-Duffy Blood Group, Chemokine Receptor (DARC) (AA 1-50) antibodyDARC 适用: 人 ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Duffy Blood Group, Chemokine Receptor (DARC) (AA 1-336) antibodyDARC 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Duffy Blood Group, Chemokine Receptor (DARC) antibody (PE)DARC 适用: 人 IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal PE
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应用备注
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DARC antibody can be used for detection of DARC by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- DARC Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- DARC antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- DARC (Duffy Blood Group, Chemokine Receptor (DARC))
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别名
- DARC
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背景
- DARC Antibody: DARC, also known as the Duffy antigen/chemokine receptor, is a seven-transmembrane protein homologous to the classical chemokine G-protein coupled receptors (GPCRs) with the exception of the motif required for G protein coupling. DARC can bind with high affinity several chemokines without transducing any signal, suggesting it may modulate the signals normally induced by these chemokines. Recently, DARC was found to interact with KAI1, a four transmembrane protein recently identified as a tumor metastasis suppressor protein. It is thought that tumor cells dislodged from the primary tumor and expressing KAI1 interact with DARC proteins expressed on vascular cells, transmitting a senescent signal to the tumor cells, while tumor cells that have lost KAI1 expression can proliferate and potentially give rise to metastases. At least three isoforms of DARC are known to exist.
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基因ID
- 2532
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UniProt
- Q16570
抗原
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