STING/TMEM173 抗体 (C-Term)
Quick Overview for STING/TMEM173 抗体 (C-Term) (ABIN6990724)
抗原
See all STING/TMEM173 (TMEM173) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 260-310, C-Term
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纯化方法
- MPYS Antibody is affinity chromatography purified via peptide column.
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免疫原
- Anti-MPYS antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human MPYS. The immunogen is located within amino acids 260-310 of MPYS.
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亚型
- IgG
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anti-Transmembrane Protein 173 (TMEM173) (AA 159-373) antibody
TMEM173 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 173 (TMEM173) antibodyTMEM173 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4H8 unconjugated
anti-Transmembrane Protein 173 (TMEM173) (AA 170-379) antibodyTMEM173 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 173 (TMEM173) (AA 284-316), (C-Term) antibodyTMEM173 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 173 (TMEM173) antibodyTMEM173 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 173 (TMEM173) (AA 311-340) antibodyTMEM173 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 173 (TMEM173) (AA 207-379) antibodyTMEM173 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 173 (TMEM173) (Internal Region) antibodyTMEM173 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 173 (TMEM173) (C-Term) antibodyTMEM173 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 173 (TMEM173) antibodyTMEM173 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 2C9 unconjugated
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应用备注
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WB: 1-2 μ,g/mL, ICC: 5 μ,g/mL, IF: 20 μ,g/mL.
Antibody validated: Western Blot in human and mouse samples, Immunocytochemistry and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- MPYS Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- MPYS antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
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别名
- MPYS
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背景
- MPYS Antibody: MPYS is a recently identified plasma membrane tetraspanner that is associated with major histocompatibility complex class II (MHC-II) and mediates its transduction of apoptotic signals. It has also been found to be associated with VISA, a mitochondrial protein that acts as an adaptor in virus-triggered signaling. MPYS also interacts with IRF3 and recruits the kinase TBK1 to the VISA-associated complex, acting as a critical mediator of virus-triggered IRF3 activation and interferon (IFN) expression. It is thought that the binding of nucleic acid to the innate immune protein RIG-I causes complex formation between RIG-I, VISA, and MPYS. This complex then recruits TBK1 to phosphorylate IRF3 which then directly activates IFN transcription. At least three isoforms of MPYS are known to exist.
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分子量
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Predicted: 42kD
Observed: 42 kD kDa -
基因ID
- 340061
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NCBI登录号
- NP_938023
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UniProt
- Q86WV6
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途径
- Activation of Innate immune Response
抗原
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