Klotho 抗体 (AA 410-460)
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- 抗原 See all Klotho (KL) 抗体
- Klotho (KL)
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抗原表位
- AA 410-460
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适用
- 小鼠, 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Klotho antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 特异性
- Three isoforms of KLOTHO are known to exist.
- 纯化方法
- KLOTHO Antibody is affinity chromatography purified via peptide column.
- 免疫原
- Anti-KLOTHO antibody was raised against a peptide corresponding to 17 amino acids near the center of human KLOTHO. The immunogen is located within amino acids 410-460 of KLOTHO.
- 亚型
- IgG
- Top Product
- Discover our top product KL Primary Antibody
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anti-Klotho (KL) (AA 516-955) antibody
KL 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Klotho (KL) (AA 401-500) antibodyKL 适用: 小鼠, 人, 大鼠 IHC (p), IHC (fro), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Klotho (KL) (AA 517-956) antibodyKL 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Klotho (KL) (AA 720-769) antibodyKL 适用: 人, 大鼠, 兔, Cow, 犬, Pig, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Klotho (KL) (AA 251-300) antibodyKL 适用: 小鼠, 人, 大鼠, 兔, 马, 犬, 豚鼠, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Klotho (KL) (N-Term) antibodyKL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Klotho (KL) (Middle Region) antibodyKL 适用: 小鼠, 人, 大鼠, 兔, 马, Cow, 犬, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Klotho (KL) (Middle Region) antibodyKL 适用: 小鼠, 人, 大鼠, 兔, 马, Cow, 犬, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Klotho (KL) (Center) antibodyKL 适用: 小鼠, 人, 大鼠 WB, IHC (p), EIA, IF 宿主: 兔 Polyclonal unconjugated
anti-Klotho (KL) (AA 765-981) antibodyKL 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: 1-4 μ,g/mL, IHC: 2.5 μ,g/mL, IF: 20 μ,g/mL.
Antibody validated: Western Blot in human, mouse and rat samples, Immunohistochemistry in mouse and rat samples, Immunofluorescence in mouse samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- KLOTHO Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- KLOTHO antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- Klotho (KL)
- 别名
- KLOTHO (KL 产品)
- 背景
- KLOTHO Antibody: KLOTHO is the systemic anti-aging hormone within the glycosidase1 superfamily. It encodes a type I membrane protein that is abundant in the kidney and brain. In mice, a deficiency in KLOTHO expression leads to various systemic phenotypes resembling human aging such as arteriosclerosis, osteoporosis, and skin atrophy together with growth retardation, short life-span and infertility. Transgenic mice overexpressing KLOTHO have an extended life span by inhibiting insulin/IGF1 signaling. KLOTHO is involved in the regulation of calcium/phosphorus homeostasis by inhibiting the synthesis of active vitamin D and identified as a potential tumor suppressor.
- 分子量
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Predicted: 116kD
Observed: 116kD kDa - 基因ID
- 9365
- NCBI登录号
- NP_004786
- UniProt
- Q9UEF7
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hormone Activity, Growth Factor Binding
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