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KDM3A 抗体 (N-Term)

This anti-KDM3A antibody is a 兔 多克隆 antibody detecting KDM3A in WB, ELISA, IF 和 IHC (p). Suitable for 人 和 大鼠.
产品编号 ABIN6990704
发货至: 中国

Quick Overview for KDM3A 抗体 (N-Term) (ABIN6990704)

抗原

See all KDM3A 抗体
KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This KDM3A antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 50-100, N-Term

    特异性

    This antibody will not cross-react with JMJD1B or JMJD1C.

    纯化方法

    JMJD1A Antibody is affinity chromatography purified via peptide column.

    免疫原

    Anti-JMJD1A antibody was raised against a peptide corresponding to 16 amino acids near the amino terminus of human JMJD1A. The immunogen is located within amino acids 50-100 of JMJD1A.

    亚型

    IgG
  • 应用备注

    WB: 1-2 μ,g/mL, IHC: 5 μ,g/mL, IF: 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples, Immunofluorescence in rat samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    JMJD1A Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    JMJD1A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))

    别名

    JMJD1A

    背景

    JMJD1A Antibody: The jumonji domain containing 1A protein (JMJD1A) was originally discovered as a testes specific gene, but has been found to be expressed in numerous tissues. JMJD1A is a histone demethylase and specifically demethylates mono- and dimethyl-H3K9. It has also been found to be a novel interaction partner with ER71, a transcription factor expressed in the testes of adult mice and during embryogenesis. JMJD1A is also a downstream gene of STAT3, a protein that has been found to be important in the maintenance of mouse embryonic stem (mES) cells, and decreased JMJD1A expression correlated with the differentiation of cultured mES cells following the removal of the cytokine LIF. These findings suggest that JMJD1A might be a critical signaling molecule underlying the maintenance of pluripotency in embryonic stem cells. At least two isoforms of JMJD1A are known to exist.

    分子量

    Predicted: 147kD

    Observed: 147kD kDa

    基因ID

    55818

    NCBI登录号

    NP_060903

    UniProt

    Q9Y4C1

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Warburg Effect
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