FAF1 抗体 (C-Term)
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北京 101111
Quick Overview for FAF1 抗体 (C-Term) (ABIN6990696)
抗原
See all FAF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- FAF1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- FAF1 antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human FAF1. The immunogen is located within the last 50 amino acids of FAF1.
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亚型
- IgG
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anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) antibody
FAF1 适用: 人 WB, IHC (f) 宿主: 小鼠 Monoclonal CPTC-FAF1-2 unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) antibodyKD Validated FAF1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB8245 unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) (AA 551-650) antibodyFAF1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A10 unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) (AA 1-650) antibodyFAF1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) (AA 1-650) antibodyFAF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) (AA 551-650) antibodyFAF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) (AA 490-629) antibodyFAF1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) (C-Term) antibodyFAF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) antibodyFAF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) (AA 1-280) antibodyFAF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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FAF1 antibody can be used for detection of FAF1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- FAF1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- FAF1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))
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别名
- FAF1
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背景
- FAF1 Antibody: Fas-associated protein 1 (FAF1) was initially identified as a Fas-binding pro-apoptotic protein that is component of the death-inducing signaling complex in Fas-mediated apoptosis. FAF1 can also induce apoptosis in the absence of extrinsic death signals when overexpressed although it does not contain typical death motifs such as the death domain, death effector domain, and caspase recruitment domain. Overexpression of FAF1 also decreases the basal level of NF-κ,B activity in transfected 293 cells, inhibits NF-κ,B activity induced by TNF-α, IL-1β, and lipopolysaccharide, and prevents NF-κ,B translocation to the nucleus, suggesting that another role of FAF1 is to negatively regulate the activity of NF-κ,B. FAF1 can also interact with the inflammatory signaling PYRIN-containing Apaf-1-like proteins (PYPAFs, also called NALPs) such as PYPAF1, PYPAF2 (NALP2), and PYPAF7, suggesting FAF1 may also be involved in the inflammation pathway. Multiple differentially spliced isoforms of FAF1 are known to exist.
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分子量
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Predicted: 74 kDa
Observed: 80 kDa -
基因ID
- 11124
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NCBI登录号
- NP_008982
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UniProt
- Q9UNN5
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途径
- Maintenance of Protein Location
抗原
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