FAF1 抗体
-
- 抗原 See all FAF1 抗体
- FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This FAF1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- In contrast to growth factors which promote cell proliferation, FAS ligand (FAS-L) and the tumor necrosis factors (TNFs) rapidly induce apoptosis. Cellular response to FAS-L and TNF is mediated by structurally related receptors containing a conserved 'death domain' and belonging to the TNF receptor superfamily. TRADD, FADD and RIP are FAS/TNF-RI interacting proteins that contain a death domain homologous region (DDH). TRADD (TNF-RI-associated death domain) and FADD (FAS-associated death domain) associate with the death domains of both FAS and TNF-RI via their DDH regions, while RIP associates exclusively with FAS. An additional FAS interacting protein designated FAF1, for FAS-associated protein factor-1, binds with the cytoplasmic tail of wildtype but not LPR mutant FAS. When overexpressed in cells, FAF1 enhances the efficiency of FAS-mediated apoptosis. In contrast to TRADD, FADD and RIP, FAF1 lacks a DDH and cannot induce apoptosis independently of FAS activation.
- 交叉反应 （详细）
- Human,
- 纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
- 免疫原
- Recombinant human full-length FAF1 protein
- 克隆位点
- CPTC-FAF1-2
- 亚型
- IgG2b
-
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) (AA 1-650) antibody
FAF1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) (AA 551-650) antibodyFAF1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A10 unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) (AA 1-650) antibodyFAF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) (AA 551-650) antibodyFAF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) (AA 490-629) antibodyFAF1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) (C-Term) antibodyFAF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) antibodyFAF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) (AA 1-650) antibodyFAF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G6 unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) (AA 1-280) antibodyFAF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) (Middle Region) antibodyFAF1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 犬 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
Positive Control: HEK293, MCF-7, HeLa whole cell lysate. Human testis, prostate, breast carcinoma or colon carcinoma.
Known Application: Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
-
- 浓度
- 200 μg/mL
- 缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
- 有效期
- 24 months
-
- 抗原
- FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))
- 别名
- FAF1 (FAF1 产品)
- 别名
- faf1 antibody, MGC53741 antibody, MGC80303 antibody, FAF1 antibody, zgc:55752 antibody, wu:fc25h12 antibody, HFAF1s antibody, UBXD12 antibody, UBXN3A antibody, hFAF1 antibody, AA408698 antibody, Dffrx antibody, Fam antibody, Fas (TNFRSF6) associated factor 1 S homeolog antibody, Fas (TNFRSF6) associated factor 1 L homeolog antibody, Fas associated factor 1 antibody, Fas (TNFRSF6) associated factor 1 antibody, Fas-associated factor 1 antibody, faf1.S antibody, faf1.L antibody, FAF1 antibody, faf1 antibody, Faf1 antibody
- 背景
-
CGI-03, FAS-associated factor 1, HFAF1s, UBX domain-containing protein 12, UBX domain-containing protein 3A,Fas (TNFRSF6) associated factor 1
Cellular localisation: Nucleus. - 分子量
- 75-80kDa
- 基因ID
- 11124, 530402
- UniProt
- Q9UNN5
- 途径
- Maintenance of Protein Location
-
