HRK 抗体
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北京 101111
Quick Overview for HRK 抗体 (ABIN6990622)
抗原
See all HRK 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Hrk Antibody is affinity chromatography purified via peptide column.
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免疫原
- HRK antibody was raised against a 15 amino acid synthetic peptide from near the center of human Hrk. The immunogen is located within the last 50 amino acids of Hrk.
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亚型
- IgG
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anti-Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK) (Center) antibody
HRK 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK) antibodyHRK 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK) (AA 1-50) antibodyHRK 适用: 小鼠, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK) (N-Term) antibodyHRK 适用: 人, Cow, 犬, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK) (AA 15-50) antibodyHRK 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB04688 unconjugated
anti-Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK) (N-Term) antibodyHRK 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK) (BH3 Domain) antibodyHRK 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Hrk antibody can be used for the detection of Hrk by Western blot at 2.5 - 5 μ,g/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Hrk Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Hrk antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))
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别名
- Hrk
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背景
- Hrk Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Hrk, a pro-apoptotic member of the Bcl-2 homology domain-3 (BH3)-only group of the Bcl-2 family of proteins, was also identified as novel protein induced during programmed neuronal death. It lacks significant homology to other Bcl-2 family members except for an 8-amino acid region that is similar to the BH3 motif of Bik. Hrk regulates apoptosis through interaction with the anti-apoptotic proteins Bcl-2 and Bcl-XL via this domain. It does not interact with the pro-apoptotic proteins Bax, Bak, or Bcl-XS. Hrk localizes to mitochondrial membranes in a pattern similar to that previously reported for Bcl-2 and Bcl-XL.
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分子量
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Predicted: 10 kDa
Observed: 12 kDa -
基因ID
- 8739
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NCBI登录号
- NP_003797
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UniProt
- O00198
抗原
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