HRK 抗体 (N-Term)
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北京 101111
Quick Overview for HRK 抗体 (N-Term) (ABIN2782598)
抗原
See all HRK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- HRK Antibody - N-terminal region
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序列
- MCPCPLHRGR GPPAVCACSA GRLGLRSSAA QLTAARLKAL GDELHQRTMW
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预测反应
- Cow: 100%, Dog: 100%, Human: 100%, Mouse: 83%, Rabbit: 100%, Rat: 83%
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产品特性
- This is a rabbit polyclonal antibody against HRK. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human HRK
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46364-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "High CIP2A levels correlate with an antiapoptotic phenotype that can be overcome by targeting BCL-XL in chronic myeloid leukemia." in: Leukemia, Vol. 30, Issue 6, pp. 1273-81, (2016) (PubMed).
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- HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))
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别名
- HRK
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背景
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Background Information: Activator of apoptosis Hrk regulates apoptosis through interaction with death-repressor proteins Bcl-2 and Bcl-X(L). The HRK protein lacks significant homology to other BCL2 family members except for an 8-amino acid region that was similar to the BCL2 hom
Gene Name: Harakiri, BCL2 interacting protein (contains only BH3 domain)
Alternative Symbols: DP5, HARAKIRI
Protein Name: Activator of apoptosis harakiri
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分子量
- 10kDa
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基因ID
- 8739
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NCBI登录号
- NP_003797
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UniProt
- O00198
抗原
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