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XBP1 抗体 (C-Term)

XBP1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990606
发货至: 中国
  • 抗原 See all XBP1 抗体
    XBP1 (X-Box Binding Protein 1 (XBP1))
    抗原表位
    • 16
    • 16
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 67
    • 41
    • 9
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    人, 小鼠, 大鼠
    宿主
    • 66
    • 11
    • 1
    克隆类型
    • 67
    • 11
    多克隆
    标记
    • 41
    • 7
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This XBP1 antibody is un-conjugated
    应用范围
    • 72
    • 43
    • 28
    • 19
    • 14
    • 13
    • 12
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    纯化方法
    XBP-1 Antibody is affinity chromatography purified via peptide column.
    免疫原
    XBP-1 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human XBP-1. The immunogen is located within the last 50 amino acids of XBP-1.
    亚型
    IgG
    Top Product
    Discover our top product XBP1 Primary Antibody
  • 应用备注
    XBP-1 antibody can be used for the detection of XBP-1 by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    XBP-1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    XBP-1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    XBP1 (X-Box Binding Protein 1 (XBP1))
    别名
    XBP-1 (XBP1 产品)
    别名
    treb5 antibody, xXBP1 antibody, xbp2 antibody, XBP1P1 antibody, XBPP1 antibody, xbp1 antibody, TREB5 antibody, XBP-1 antibody, XBP2 antibody, D11Ertd39e antibody, TREB-5 antibody, HTF antibody, cb918 antibody, id:ibd1195 antibody, trebf antibody, wu:fb02h05 antibody, wu:fb63f10 antibody, xbp1a antibody, xbp1b antibody, X-box binding protein 1 antibody, X-box binding protein 1 L homeolog antibody, xbp1 antibody, XBP1 antibody, Xbp1 antibody, xbp1.L antibody
    背景
    XBP-1 Antibody: X box binding protein 1 (XBP-1) is a key protein in the mammalian unfolded protein response (UPR) that protects the cell against the stress of malfolded proteins in the endoplasmic reticulum (ER). Upon sensing unfolded proteins, an ER transmembrane endonuclease and kinase termed IRE1p is activated and excises an intron from XBP-1 mRNA. The spliced XBP-1 mRNA results in a 371 amino acid protein (XBP-1s) which is then translocated to the nucleus where it binds to the regulatory elements of downstream genes. Together with other UPR transcription factors such as ATF6, XBP-1 stimulates the production of ER stress proteins including the ER resident protein chaperones glucose regulated protein (GRP) 78 and GRP94.
    基因ID
    7494
    UniProt
    P17861
    途径
    ER-Nucleus Signaling, Unfolded Protein Response
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