ATF6 抗体 (N-Term)
Quick Overview for ATF6 抗体 (N-Term) (ABIN6990605)
抗原
See all ATF6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-80, N-Term
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纯化方法
- ATF6 Antibody is affinity chromatography purified via peptide column.
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免疫原
- ATF6 antibody was raised against a 17 amino acid synthetic peptide from near the amino terminus of human ATF6. The immunogen is located within amino acids 30 - 80 of ATF6.
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亚型
- IgG
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anti-Activating Transcription Factor 6 (ATF6) (AA 1-190) antibody
ATF6 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 6 (ATF6) (AA 1-377) antibodyATF6 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 6 (ATF6) (AA 437-449) antibodyVerified ATF6 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Activating Transcription Factor 6 (ATF6) (AA 301-400) antibodyATF6 适用: 人 WB, ELISA, IF (p), IF (cc), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 6 (ATF6) (AA 350-377) antibodyATF6 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22035 unconjugated
anti-Activating Transcription Factor 6 (ATF6) (AA 350-377) antibodyATF6 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 6 (ATF6) (AA 423-646) antibodyATF6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 6 (ATF6) (AA 91-193) antibodyATF6 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D5 unconjugated
anti-Activating Transcription Factor 6 (ATF6) (N-Term) antibodyATF6 适用: 人 WB, IP 宿主: 小鼠 Monoclonal 1-7 unconjugated
anti-Activating Transcription Factor 6 (ATF6) (N-Term) antibodyATF6 适用: 人, 小鼠 WB, IP 宿主: 小鼠 Monoclonal 37-1 unconjugated
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应用备注
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WB: 0.5-1 μ,g/mL, IHC: 5 μ,g/mL, IF: 20 μ,g/mL.
Antibody validated: Western Blot in human, mouse and rat samples, Immunohistochemistry in mouse and rat samples, Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- ATF6 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- ATF6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- ATF6 (Activating Transcription Factor 6 (ATF6))
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别名
- ATF6
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背景
- ATF6 Antibody: Disruptions of protein folding and maturation in the endoplasmic reticulum (ER) result in the activation of the unfolded protein response (UPR), an integrated cellular signaling pathway that transmits information from the ER lumen to the cytoplasm and nucleus. Activating transcription factor 6 (ATF6) as well as the ER-transmembrane protein kinases IRE1p and PERK are the major transducers of the UPR. ATF6 is an ER transmembrane protein that is normally bound to the ER chaperone GRP78, but upon ER stress is released from GRP78 and proteolytically cleaved to yield a cytosolic fragment which then migrates to the nucleus, and together with the transcription factor XBP-1, activates transcription of UPR-responsive genes. ATF6 has two isoforms (ATF6α, and ATF6β,), only ATF6α, is recognized by this antibody.
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基因ID
- 22926
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NCBI登录号
- NP_031374
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UniProt
- P18850
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途径
- ER-Nucleus Signaling, Unfolded Protein Response
抗原
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