DR4 抗体 (N-Term)
Quick Overview for DR4 抗体 (N-Term) (ABIN6990591)
抗原
See all DR4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- DR4 antibody has no cross reaction to DR5.
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纯化方法
- DR4 Antibody is Antibody is DEAE purified.
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免疫原
- Anti-DR4 antibody was raised against a peptide corresponding to 20 amino acids near the amino terminus of human DR4. The immunogen is located within the first 50 amino acids of DR4.
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亚型
- IgG
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anti-Drought-Repressed 4 Protein (DR4) (AA 401-468) antibody
DR4 适用: 人, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Drought-Repressed 4 Protein (DR4) (C-Term) antibodyDR4 适用: 人, 猴 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Drought-Repressed 4 Protein (DR4) (C-Term) antibodyDR4 适用: 人, 小鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Drought-Repressed 4 Protein (DR4) (AA 401-450) antibodyDR4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1-4 μ,g/mL, ICC: 2 μ,g/mL, IF: 5 μ,g/mL.
Antibody validated: Western Blot in human and mouse samples, Immunocytochemistry in human samples and Immunofluorescence in human and rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- DR4 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- DR4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- DR4 (Drought-Repressed 4 Protein (DR4))
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别名
- DR4
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背景
- DR4 Antibody: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel death domain containing receptor was recently identified and designated DR4 (for death receptor 4). The ligand for this novel death receptor has been identified and termed TRAIL, which is a new member in the TNF family. DR4 is also called TRAIL receptor-1 (TRAIL-R1). DR4 is expressed in most of human tissues including spleen, peripheral blood leukocytes, small intestine and thymus. Like TNFR1, Fas and DR3, DR4 mediates apoptosis and NF-κ,B activation in many tissues and cells.
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分子量
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Predicted: 50kD
Observed: 55kD (Post-modification: 1 N-linked glycosylation) kDa -
基因ID
- 8797
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UniProt
- O00220
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途径
- Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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