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TLR3 抗体 (N-Term)

This anti-TLR3 antibody is a 兔 多克隆 antibody detecting TLR3 in WB, ELISA, ICC 和 IF. Suitable for 人 和 小鼠.
产品编号 ABIN6990586
发货至: 中国

Quick Overview for TLR3 抗体 (N-Term) (ABIN6990586)

抗原

See all TLR3 抗体
TLR3 (Toll-Like Receptor 3 (TLR3))

适用

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人, 小鼠

宿主

  • 89
  • 30
  • 5
  • 2
  • 1

克隆类型

  • 92
  • 35
多克隆

标记

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This TLR3 antibody is un-conjugated

应用范围

  • 88
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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 抗原表位

    • 16
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    AA 40-90, N-Term

    纯化方法

    TLR3 Antibody is affinity chromatography purified via peptide column.

    免疫原

    TLR3 antibody was raised against a peptide corresponding to 15 amino acids near the amino terminus of human TLR3. The immunogen is located within amino acids 40 - 90 of TLR3.

    亚型

    IgG
  • 应用备注

    TLR3 antibody can be used for detection of TLR3 by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 2 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    TLR3 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    TLR3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    TLR3 (Toll-Like Receptor 3 (TLR3))

    别名

    TLR3

    背景

    TLR3 Antibody: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR3 is known to recognize viral double-stranded (ds) RNA, a molecular pattern associated with viral infection. Recently it has been shown to recognize viruses such as Influenza A and West Nile Virus and can mediate entry of at least West Nile Virus.

    分子量

    Predicted: 88 kDa

    Observed: 91 kDa

    基因ID

    7098

    UniProt

    O15455

    途径

    TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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