TLR1 抗体 (AA 390-440)
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北京 101111
Quick Overview for TLR1 抗体 (AA 390-440) (ABIN6990584)
抗原
See all TLR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 390-440
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纯化方法
- TLR1 Antibody is Ion exchange chromatography purified.
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免疫原
- TLR1 antibody was raised against a peptide corresponding to 17 amino acids near the center of human TLR1. The immunogen is located within amino acids 390 - 440 of TLR1.
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亚型
- IgG
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应用备注
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TLR1 antibody can be used for detection of TLR1 by Western blot at 1 to 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TLR1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- TLR1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- TLR1 (Toll-Like Receptor 1 (TLR1))
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别名
- TLR1
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背景
- TLR1 Antibody: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR1 is co-expressed with TLR2 on myeloid cells of the innate immune systems in lymphoid tissue such as monocytes and dendritic cells where they form heterodimers that can recognize triacylated lipoproteins.
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分子量
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Predicted: 87 kDa
Observed: 93 kDa -
基因ID
- 7096
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UniProt
- Q15399
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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