LAMP1 抗体 (AA 230-280)
Quick Overview for LAMP1 抗体 (AA 230-280) (ABIN6990580)
抗原
See all LAMP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 230-280
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特异性
- LAMP-1 antibody is predicted to not cross-react with LAMP-2. Due to extensive post-translational modification, LAMP-1 often migrates at higher than predicted molecular weight in SDS-PAGE.
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纯化方法
- LAMP-1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- LAMP-1 antibody was raised against a 15 amino acid synthetic peptide from near the center of human LAMP-1. The immunogen is located within amino acids 230 - 280 of LAMP-1.
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亚型
- IgG
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anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) (AA 80-280) antibody
LAMP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) (AA 301-417) antibodyLAMP1 适用: 人, 小鼠, 大鼠, 猴 WB, FACS, ELISA, ICC, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) (AA 49-297) antibodyLAMP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibodyLAMP1 适用: 人, 小鼠, Non-Human Primate WB, FACS, ICC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal H4A3 unconjugated
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibodyLAMP1 适用: 大鼠 WB, IF, IP, ICC 宿主: 小鼠 Monoclonal Ly1C6 unconjugated
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) (AA 125-154) antibodyLAMP1 适用: 人, 小鼠 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibodyLAMP1 适用: 人, 小鼠, 灵长类 WB, FACS, IHC, ICC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal H4A3 unconjugated
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibody (FITC)LAMP1 适用: 小鼠 WB, FACS, IHC, IP, IHC (p), IHC (fro) 宿主: 大鼠 Monoclonal FITC
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibody (APC)LAMP1 适用: 人, 小鼠, Non-Human Primate FACS 宿主: 小鼠 Monoclonal H4A3 APC
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibodyLAMP1 适用: 人, Green Monkey WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 3C3 unconjugated
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应用备注
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LAMP-1 antibody can be used for the detection of LAMP-1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in rat samples and Immunofluorescence in human and rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- LAMP-1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- LAMP-1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
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别名
- LAMP-1
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背景
- LAMP-1 Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components and is negatively regulated by TOR (Target of rapamycin). A protein recently found to be involved in autophagy, LAMP-2, is a highly glycosylated protein associated with the lysosome. LAMP-1 shares much homology to LAMP-2 and is thought to have overlapping functions. Mice lacking LAMP-1 had very minor defects compared to those deficient in LAMP-2 expression. However, the loss of both proteins resulted in embryonic lethality, suggesting that each protein possesses some unique and necessary functions.
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分子量
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Predicted: 46 kDa
Observed: 95 kDa -
基因ID
- 3916
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NCBI登录号
- NP_005552
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UniProt
- P11279
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途径
- Autophagy
抗原
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