RAPTOR 抗体 (C-Term)
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北京 101111
Quick Overview for RAPTOR 抗体 (C-Term) (ABIN6990529)
抗原
See all RAPTOR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1140-1190, C-Term
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特异性
- Raptor has multiple isoforms that may also be recognized by antibody.
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纯化方法
- Raptor Antibody is affinity chromatography purified via peptide column.
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免疫原
- Raptor (CT) polyclonal antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of mouse Raptor. The immunogen is located within amino acids 1140 - 1190 of Raptor.
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亚型
- IgG
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anti-RAPTOR (RAPTOR) (pSer863) antibody
RAPTOR 适用: 人 WB, DB, IHC (p) 宿主: 兔 Polyclonal RB24817-24818 unconjugated
anti-RAPTOR (RAPTOR) antibodyRAPTOR 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB855 unconjugated Recombinant Antibody
anti-RAPTOR (RAPTOR) antibodyRAPTOR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 1411CT316-2-151-34 unconjugated
anti-RAPTOR (RAPTOR) (AA 101-200) antibodyRAPTOR 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-RAPTOR (RAPTOR) (pSer863) antibodyRAPTOR 适用: 人 ELISA, DB 宿主: 兔 Polyclonal unconjugated
anti-RAPTOR (RAPTOR) (C-Term) antibodyRAPTOR 适用: 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-RAPTOR (RAPTOR) (N-Term) antibodyRAPTOR 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Raptor antibody can be used for the detection of Raptor by Western blot at 2 and 4 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL.
Antibody validated: Western Blot in mouse samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Raptor Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Raptor antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- RAPTOR
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别名
- Raptor
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背景
- Raptor Antibody: The mammalian Target of Rapamycin (TOR, also known as mTOR) is an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors. Rapamycin inhibits TOR activity resulting in reduced cell growth and reduced rates of cell cycle and cell proliferation. Raptor (regulatory associated protein of TOR) is a TOR-binding protein essential for TOR signaling in vivo. It acts as a TOR scaffold protein whose binding by TOR substrates is necessary for effective TOR-catalyzed phosphorylation. These substrates include the ribosomal protein S6 kinase (RP S6K) and the eukaryotic initiation factor 4E binding protein 4EBP1, proteins necessary for cell growth and proliferation and responsive to nutrient and mitogen levels. Raptor binds these proteins through a common 5 amino acid TOR-signaling (TOS) motif, mutation of this motif prevents the TOR-dependent phosphorylation of these proteins.
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基因ID
- 74370
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UniProt
- Q8K4Q0
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途径
- Warburg Effect
抗原
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