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RAPTOR 抗体 (pSer863)

RAPTOR 适用: 人 ELISA, DB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3032433
发货至: 中国
  • 抗原 See all RAPTOR 抗体
    RAPTOR
    抗原表位
    • 15
    • 15
    • 15
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer863
    适用
    • 62
    • 45
    • 25
    • 15
    • 1
    宿主
    • 62
    • 3
    克隆类型
    • 62
    • 3
    多克隆
    标记
    • 20
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This RAPTOR antibody is un-conjugated
    应用范围
    • 30
    • 26
    • 26
    • 25
    • 8
    • 8
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    ELISA, Dot Blot (DB)
    纯化方法
    Antigen affinity purified
    免疫原
    This phospho-Raptor antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS863 of human Raptor.
    亚型
    Ig Fraction
    Top Product
    Discover our top product RAPTOR Primary Antibody
  • 应用备注
    Titration of the phospho-Raptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the phospho-Raptor antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    RAPTOR
    别名
    Raptor (RAPTOR 产品)
    别名
    KOG1 antibody, Mip1 antibody, 4932417H02Rik antibody, Rap antibody, Raptor antibody, mKIAA1303 antibody, RGD1311784 antibody, regulatory associated protein of MTOR complex 1 antibody, regulatory associated protein of MTOR, complex 1 antibody, RPTOR antibody, Rptor antibody
    背景
    Raptor participates in the FRAP1 pathway and associates in a near stoichiometric ratio with FRAP1 to form a nutrient-sensitive complex (NSC). It plays a pivotal role as a scaffold protein in the FRAP1-signaling pathway and this interaction is essential for the catalyzed phosphorylation of EIF4EBP1. It has a positive role in nutrient-stimulated signaling to the downstream effector RPS6KB1. Under nutrient-deprived conditions, raptor serves as a negative regulator of FRAP1 kinase activity. Regulation of the interaction with FRAP1 is a critical mechanism by which cells coordinate the rate of cell growth and maintenance of cell size with different environmental conditions.
    UniProt
    Q8N122
    途径
    Warburg Effect
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