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Caspase 7 抗体 (C-Term)

This anti-Caspase 7 antibody is a 兔 多克隆 antibody detecting Caspase 7 in WB, ELISA 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6990520
发货至: 中国

Quick Overview for Caspase 7 抗体 (C-Term) (ABIN6990520)

抗原

See all Caspase 7 (CASP7) 抗体
Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

适用

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人, 小鼠, 大鼠

宿主

  • 99
  • 12
  • 1

克隆类型

  • 97
  • 15
多克隆

标记

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This Caspase 7 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 16
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    C-Term

    特异性

    Depending on cell lines or tissues used, other cleavage products may be observed.

    纯化方法

    Caspase-7 Antibody is affinity chromatography purified via peptide column.

    免疫原

    Caspase-7 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human Caspase-7. The immunogen is located within the last 50 amino acids of Caspase-7.

    亚型

    IgG
  • 应用备注

    Casp-7 antibody can be used for the detection of Caspase-7 by Western blot at 0.5 to 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Caspase-7 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    Caspase-7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

    别名

    Caspase-7

    背景

    Caspase-7 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death. Caspase-7 is an executioner caspase that was identified based on its homology with caspases 1 and 3, as well as the C. elegans cell death protein CED-3. Alternative splicing of Caspase-7 mRNA results in the production of 3 distinct isoforms. Caspase-7 activity can be directly inhibited by XIAP expression.

    基因ID

    840

    UniProt

    P55210

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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