TAB2 抗体 (C-Term)
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北京 101111
Quick Overview for TAB2 抗体 (C-Term) (ABIN6990488)
抗原
See all TAB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- TAB2 antibody is human specific. TAB2 antibody is predicted not to cross-react with other TAB proteins.
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纯化方法
- TAB2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- TAB2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human TAB2. The immunogen is located within the last 50 amino acids of TAB2.
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亚型
- IgG
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anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (N-Term) antibody
TAB2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (N-Term) antibodyTAB2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Pig, Bat, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) antibodyTAB2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3B5 unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) antibodyTAB2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3B5 unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (AA 350-693) antibodyTAB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (AA 646-680), (C-Term) antibodyTAB2 适用: 大鼠 WB 宿主: 兔 Polyclonal RB52974 unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (Internal Region) antibodyTAB2 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (AA 1-693) antibodyTAB2 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (AA 1-693) antibodyTAB2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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TAB2 antibody can be used for detection of TAB2 by immunohistochemistry at 5 μ,g/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TAB2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- TAB2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- TAB2 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))
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别名
- TAB2
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背景
- TAB2 Antibody: TAB2 is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation NF-kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKL through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. Recent experiments have shown that TAB2 and the related protein TAB3 constitutitvely interact with the autophagy mediator Beclin-1, upon induction of autophagy, these proteins dissociate from Beclin-1 and bind TAK1. Overexpression of TAB2 and TAB3 inhibit autophagy, while their depletion triggers it, suggesting that TAB2 and TAB3 act as a control point for autophagy.
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基因ID
- 23118
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NCBI登录号
- NP_055908
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UniProt
- Q9NYJ8
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途径
- TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Ubiquitin Proteasome Pathway
抗原
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