ECSIT 抗体 (C-Term)
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Quick Overview for ECSIT 抗体 (C-Term) (ABIN6990485)
抗原
See all ECSIT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 290-340, C-Term
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纯化方法
- ECSIT Antibody is Ion exchange chromatography purified.
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免疫原
- ECSIT antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human ECSIT. The immunogen is located within amino acids 290 - 340 of ECSIT.
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亚型
- IgG
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anti-ECSIT (ECSIT) (AA 185-431) antibody
ECSIT 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ECSIT (ECSIT) (AA 51-100) antibodyECSIT 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-ECSIT (ECSIT) (AA 20-431) antibodyECSIT 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 1B8 unconjugated
anti-ECSIT (ECSIT) (AA 241-290) antibodyECSIT 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-ECSIT (ECSIT) (Middle Region) antibodyECSIT 适用: 人, 小鼠, 大鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-ECSIT (ECSIT) antibodyECSIT 适用: 人 WB, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-ECSIT (ECSIT) (C-Term) antibodyECSIT 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ECSIT antibody can be used for detection of ECSIT by Western blot at 0.5 to 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- ECSIT Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- ECSIT antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- ECSIT
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别名
- ECSIT
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背景
- ECSIT Antibody: Activation of NF-κ,B as a result of Toll-like receptor (TLR) and IL-1 receptor signaling is a major component of innate immune responses. Signals from these receptors are relayed by a number of adapter molecules such as TRIF, TIRAP, and MyD88 to kinases such as IRAK and other intermediates such as TNF receptor associated factor (TRAF)-6. ECSIT (evolutionarily conserved signaling intermediate in Toll pathways) was initially identified as a cytoplasmic protein interacting specifically with TNF receptor associated factor (TRAF)-6 in the TLR pathway. Recently however, ECSIT has also been shown to be required for bone morphogenetic protein (Bmp) signaling and mesoderm formation during mouse embryogenesis, indicating the possibility of cross-talk between the TLR/IL-B and Bmp signaling pathways.
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基因ID
- 51295
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NCBI登录号
- NP_057665
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UniProt
- Q9BQ95
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途径
- TLR signaling, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
抗原
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