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BOK 抗体 (N-Term)

This anti-BOK antibody is a 兔 多克隆 antibody detecting BOK in ELISA 和 IHC (p). Suitable for 人.
产品编号 ABIN6990478
发货至: 中国

Quick Overview for BOK 抗体 (N-Term) (ABIN6990478)

抗原

See all BOK 抗体
BOK (BCL2-Related Ovarian Killer (BOK))

适用

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宿主

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克隆类型

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多克隆

标记

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This BOK antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    N-Term

    特异性

    At least three isoforms of BOK are known to exist, this antibody will not detect the smallest isoform. BOK antibody is predicted to not cross-react with other Bcl-2 protein family members

    纯化方法

    BOK Antibody is affinity chromatography purified via peptide column.

    免疫原

    BOK antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BOK. The immunogen is located within the first 50 amino acids of BOK.

    亚型

    IgG
  • 应用备注

    BOK antibody can be used for detection of BOK by immunohistochemistry at 5 μ,g/mL.

    Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    BOK Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    BOK antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    BOK (BCL2-Related Ovarian Killer (BOK))

    别名

    BOK

    背景

    BOK Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. BOK, a pro-apoptotic Bcl-2 family member, was initially identified in the ovary, and was found to interact with other Bcl-2 family members such as Mcl-1 and Bfl-1. BOK expression is high during early placental development, suggesting that it may also play a role in regulating trophoblast cell proliferation.

    基因ID

    666

    UniProt

    Q9UMX3

    途径

    Positive Regulation of Endopeptidase Activity
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