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TLR7 抗体 (AA 420-470)

This anti-TLR7 antibody is a 兔 多克隆 antibody detecting TLR7 in WB, ELISA 和 ICC. Suitable for 人 和 小鼠.
产品编号 ABIN6990451
发货至: 中国

Quick Overview for TLR7 抗体 (AA 420-470) (ABIN6990451)

抗原

See all TLR7 抗体
TLR7 (Toll-Like Receptor 7 (TLR7))

适用

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人, 小鼠

宿主

  • 92
  • 20

克隆类型

  • 80
  • 31
  • 1
多克隆

标记

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This TLR7 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
  • 抗原表位

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    AA 420-470

    纯化方法

    TLR7 Antibody is affinity chromatography purified via peptide column.

    免疫原

    TLR7 antibody was raised against a peptide corresponding to 14 amino acids near the center of mouse TLR7. The immunogen is located within amino acids 420 - 470 of TLR7.

    亚型

    IgG
  • 应用备注

    TLR7 antibody can be used for detection of TLR7 by Western blot at 0.5 to 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    TLR7 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    TLR7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    TLR7 (Toll-Like Receptor 7 (TLR7))

    别名

    TLR7

    背景

    TLR7 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR7, like TLRs 3, 8, and 9, is localized in intracellular acidic compartments such as the phagolysosome and will recognize some single-stranded RNA viruses such as vesicular stomatitis virus (VSV) and influenza virus. Activation of TLR7 by VSV results in stimulation of the immune response including IFNalpha secretion, suggesting the importance of TLR7 in virus recognition.

    分子量

    Predicted: 116 kDa

    Observed: 135 kDa

    基因ID

    170743

    NCBI登录号

    NP_573474

    UniProt

    P58681

    途径

    TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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