CARD8 抗体 (C-Term)
Quick Overview for CARD8 抗体 (C-Term) (ABIN6990435)
抗原
See all CARD8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- CARD8 Antibody is affinity chromatography purified via peptide column.
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免疫原
- CARD8 antibody was raised against a synthetic peptide corresponding to amino acids at the C-terminus of human CARD8. The immunogen is located within the last 50 amino acids of CARD8.
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亚型
- IgG
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anti-Caspase Recruitment Domain Family, Member 8 (CARD8) antibody
CARD8 适用: 人 WB, ICC, IP, FACS, DB 宿主: 小鼠 Monoclonal 2108C2a unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) (AA 1-200) antibodyCARD8 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) (AA 1-392) antibodyCARD8 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) (AA 1-392) antibodyCARD8 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) antibodyCARD8 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) (C-Term) antibodyCARD8 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) (AA 1-200) antibodyCARD8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 8 (CARD8) antibodyCARD8 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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CARD8 antibody can be used for detection of CARD8 by Western blot at 1 -2 μ,g/mL. An approximate 45 kDa can be detected. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- CARD8 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- CARD8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))
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别名
- CARD8
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背景
- CARD8 Antibody: Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD8. This protein interacts with DRAL, a p53-responsive protein implicated in the induction of apoptosis, and caspase-1 and its related proteins ICEBERG and pesudo-ICE. Although there are conflicting reports on whether CARD8 acts a pro- or anti-apoptotic protein, it has been suggested that it functions as an adaptor molecule regulating caspase-1 and NF-κ,B activation.
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分子量
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Predicted: 47 kDa
Observed: 47 kDa -
基因ID
- 22900
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UniProt
- Q9Y2G2
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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