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TLR4 抗体 (N-Term)

This anti-TLR4 antibody is a 兔 多克隆 antibody detecting TLR4 in WB, ELISA, IF, ICC 和 IHC (p). Suitable for 人.
产品编号 ABIN6990423
发货至: 中国

Quick Overview for TLR4 抗体 (N-Term) (ABIN6990423)

抗原

See all TLR4 抗体
TLR4 (Toll-Like Receptor 4 (TLR4))

适用

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克隆类型

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多克隆

标记

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This TLR4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    AA 30-80, N-Term

    纯化方法

    TLR4 Antibody is Ion exchange chromatography purified.

    免疫原

    TLR4 antibody was raised against a peptide corresponding to 15 amino acids near the amino-terminus of human TLR4. The immunogen is located within amino acids 30 - 80 of TLR4.

    亚型

    IgG
  • 应用备注

    TLR4 antibody can be used for detection of TLR4 by Western blot at 2 to 4 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2 μ,g/mL and Immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    TLR4 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    TLR4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    TLR4 (Toll-Like Receptor 4 (TLR4))

    别名

    TLR4

    背景

    TLR4 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-κ,B. Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram-negative sepsis.

    分子量

    Predicted: 92 kDa

    Observed: 94 kDa

    基因ID

    7099

    NCBI登录号

    NP_612564

    UniProt

    O00206

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
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