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TLR4 抗体 (C-Term)

This anti-TLR4 antibody is a 兔 多克隆 antibody detecting TLR4 in ELISA 和 IHC (p). Suitable for 人.
产品编号 ABIN6990422
发货至: 中国

Quick Overview for TLR4 抗体 (C-Term) (ABIN6990422)

抗原

See all TLR4 抗体
TLR4 (Toll-Like Receptor 4 (TLR4))

适用

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宿主

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克隆类型

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多克隆

标记

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This TLR4 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    C-Term

    特异性

    TLR4 antibody is predicted to not cross-react with other TLR protein family members.

    纯化方法

    TLR4 Antibody is affinity chromatography purified via peptide column.

    免疫原

    TLR4 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human TLR4. The immunogen is located within the last 50 amino acids of TLR4.

    亚型

    IgG
  • 应用备注

    TLR4 antibody can be used for detection of TLR4 by immunohistochemistry at 5 μ,g/mL.

    Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    TLR4 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    TLR4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    TLR4 (Toll-Like Receptor 4 (TLR4))

    别名

    TLR4

    背景

    TLR4 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-κ,B. Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram-negative sepsis.

    基因ID

    7099

    NCBI登录号

    NP_612564

    UniProt

    O00206

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
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