HTRA2 抗体 (C-Term)
Quick Overview for HTRA2 抗体 (C-Term) (ABIN6990409)
抗原
See all HTRA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 70-120, C-Term
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纯化方法
- OMI Antibody is Ion exchange chromatography purified.
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免疫原
- OMI antibody was raised against a peptide corresponding to 16 amino acids near the C-terminus of human Omi. The immunogen is located within amino acids 70 - 120 of OMI.
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亚型
- IgG
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anti-HtrA Serine Peptidase 2 (HTRA2) (AA 278-458) antibody
HTRA2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 6H7A8 unconjugated
anti-HtrA Serine Peptidase 2 (HTRA2) (AA 334-458) antibodyHTRA2 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 2 (HTRA2) (AA 359-458) antibodyHTRA2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4F10 unconjugated
anti-HtrA Serine Peptidase 2 (HTRA2) antibodyHTRA2 适用: 人 WB, IP, IHC (p) 宿主: 小鼠 Monoclonal 18-01-83 unconjugated
anti-HtrA Serine Peptidase 2 (HTRA2) (AA 231-330) antibodyHTRA2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 2 (HTRA2) antibodyHTRA2 适用: 人 WB, IP 宿主: 小鼠 Monoclonal 8G11-4B8-4F10-G5 unconjugated
anti-HtrA Serine Peptidase 2 (HTRA2) (AA 335-350) antibodyHTRA2 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 196C429 unconjugated
anti-HtrA Serine Peptidase 2 (HTRA2) (AA 73-102), (N-Term) antibodyHTRA2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33645 unconjugated
anti-HtrA Serine Peptidase 2 (HTRA2) antibodyHTRA2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 2 (HTRA2) (S306A) antibodyHTRA2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B3 unconjugated
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应用备注
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OMI antibody can be used for detection of OMI by Western blot at 0.5 to 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- OMI Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- OMI antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
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别名
- OMI
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背景
- OMI Antibody: Inhibitor of apoptosis proteins (IAPs) were initially identified in baculoviruses as proteins that inhibit apoptosis of the host cells to allow time for viral replication. Cellular homologues containing at least one baculoviral IAP repeat (BIR) motif essential for their anti-apoptosis activity have been identified in yeasts and higher organisms and often act by binding and inhibiting processed caspases. The activity of these proteins can be modulated by the expression of proteins such as Smac/DIABLO and XAF-1 which displace or prevent the binding of caspases by IAPs. Recently, a mitochondrial serine protease termed Omi/HtrA2 has been found to bind IAPs. Similar to Smac, Omi possesses a conserved IAP-binding motif, but acts to cleave IAPs to irreversibly inactivate IAPs and promote apoptosis.
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基因ID
- 27429
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UniProt
- O43464
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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