BCL2L13 抗体 (AA 280-330)
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北京 101111
Quick Overview for BCL2L13 抗体 (AA 280-330) (ABIN6990398)
抗原
See all BCL2L13 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 280-330
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纯化方法
- Bcl-rambo Antibody is affinity chromatography purified via peptide column.
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免疫原
- Bcl-rambo antibody was raised against a 15 amino acid synthetic peptide from near the center of human Bcl-rambo. The immunogen is located within amino acids 280 - 330 of Bcl-rambo.
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亚型
- IgG
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anti-BCL2-Like 13 (Apoptosis Facilitator) (BCL2L13) (AA 1-300) antibody
BCL2L13 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 13 (Apoptosis Facilitator) (BCL2L13) (AA 1-485) antibodyBCL2L13 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G11 unconjugated
anti-BCL2-Like 13 (Apoptosis Facilitator) (BCL2L13) (AA 395-444) antibodyBCL2L13 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 13 (Apoptosis Facilitator) (BCL2L13) (Intermediate Domain) antibodyBCL2L13 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 13 (Apoptosis Facilitator) (BCL2L13) antibodyBCL2L13 适用: 人 WB 宿主: 小鼠 Monoclonal 25GB8080 unconjugated
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应用备注
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Bcl-rambo antibody can be used for the detection of Bcl-rambo by Western blot at 2 and 4 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Bcl-rambo Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Bcl-rambo antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- BCL2L13 (BCL2-Like 13 (Apoptosis Facilitator) (BCL2L13))
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别名
- Bcl-rambo
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背景
- Bcl-rambo Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Members of the Bcl-2 family are known to be critical regulators of this process. These proteins are characterized by the presence of several conserved motifs termed Bcl-2 homology (BH) domains. A novel, widely expressed member termed Bcl-rambo was recently identified. This protein is localized to mitochondria in mammalian cells and its overexpression induces apoptosis which could be blocked by co-expression of inhibitor of apoptosis proteins (IAPs) such as XIAP, cIAP1, and cIAP2. Bcl-rambo shows overall homology to the anti-apoptotic members containing BH motifs, but unlike Bcl-2, the C-terminal membrane anchor of Bcl-rambo is preceded by a unique 250 amino acid insertion. This region by itself can induce apoptosis more efficiently than the Bcl-2 homology regions, suggesting that Bcl-rambo may be important other pro-apoptotic pathways.
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基因ID
- 23786
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UniProt
- Q9BXK5
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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