ILP-2 抗体 (N-Term)
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北京 101111
Quick Overview for ILP-2 抗体 (N-Term) (ABIN6990397)
抗原
See all ILP-2 (BIRC8) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- ILP-2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- ILP-2 antibody was raised with against a synthetic peptide corresponding to amino acids near the amino terminus of human ILP-2. The immunogen is located within the first 50 amino acids of ILP-2.
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亚型
- IgG
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anti-Baculoviral IAP Repeat-Containing 8 (BIRC8) (N-Term) antibody
BIRC8 适用: 人, 大鼠, 小鼠 WB, ICC, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 8 (BIRC8) (AA 1-236) antibodyBIRC8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 8 (BIRC8) antibodyBIRC8 适用: 人, 大鼠, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ILP-2 antibody can be used for detection of ILP-2 by Western blot at 1 μ,g/mL. A band at approximately 33 kDa can be detected. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- ILP-2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- ILP-2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- ILP-2 (BIRC8) (Baculoviral IAP Repeat-Containing 8 (BIRC8))
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别名
- ILP-2
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背景
- ILP-2 Antibody: Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind to and inhibits specific proteases. A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2. ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues. ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibits apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9. These results suggest that ILP-2 is a novel IAP family member with restricted specificity for caspase-9.
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分子量
- 33 kDa
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基因ID
- 112401
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NCBI登录号
- NP_203127
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UniProt
- Q96P09
抗原
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