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CASP14 抗体 (C-Term)

This anti-CASP14 antibody is a 兔 多克隆 antibody detecting CASP14 in WB, ELISA 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6990387
发货至: 中国

Quick Overview for CASP14 抗体 (C-Term) (ABIN6990387)

抗原

See all CASP14 抗体
CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))

适用

人, 小鼠, 大鼠

宿主

  • 45
  • 7
  • 1

克隆类型

  • 37
  • 16
多克隆

标记

  • 39
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This CASP14 antibody is un-conjugated

应用范围

  • 36
  • 21
  • 17
  • 16
  • 9
  • 6
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    纯化方法

    Caspase-14 Antibody is affinity chromatography purified via peptide column.

    免疫原

    Caspase-14 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human caspase-14. The immunogen is located within the last 50 amino acids of Caspase-14.

    亚型

    IgG
  • 应用备注

    Caspase-14 antibody can be used for the detection of caspase-14 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Caspase-14 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    Caspase-14 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))

    别名

    Caspase-14

    背景

    Caspase-14 Antibody: Caspases are a family of cysteine proteases that can be divided into apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1b and IL-18. Caspase-14 is highly expressed in embryonic but not adult tissues. It is processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in the keratinocyte terminal differentiation, which is important for the formation of the skin barrier.

    分子量

    Predicted: 28 kDa

    Observed: 27 kDa

    基因ID

    23581

    UniProt

    P31944
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