IL27 Receptor alpha 抗体 (C-Term)
Quick Overview for IL27 Receptor alpha 抗体 (C-Term) (ABIN6990378)
抗原
See all IL27 Receptor alpha (IL27RA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- TCCR Antibody is affinity chromatography purified via peptide column.
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免疫原
- TCCR antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of human TCCR precursor. The sequence is identical to that of mouse TCCR. The immunogen is located within the last 50 amino acids of TCCR.
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亚型
- IgG
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应用备注
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TCCR antibody can be used for detection of TCCR by Western blot at 1 μ,g/mL. An approximately 70 kDa band can be detected. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TCCR Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- TCCR antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- IL27 Receptor alpha (IL27RA) (Interleukin 27 Receptor, alpha (IL27RA))
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别名
- TCCR
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背景
- TCCR Antibody: Upon antigen challenge, T-helper cells differentiate into two functional distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-gamma and lymphotoxin-beta that augment cell mediated immune response while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned. It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1. TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-gamma and Th1-dependent antibody IgG2a. TCCR is predominately expressed in thymus, spleen, lymph notes and peripheral blood leukocytes.
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分子量
- 70 kDa
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基因ID
- 9466
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NCBI登录号
- NP_004834
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UniProt
- Q6UWB1
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途径
- Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response
抗原
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