IL27 Receptor alpha 抗体 (N-Term)
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- 抗原 See all IL27 Receptor alpha (IL27RA) 抗体
- IL27 Receptor alpha (IL27RA) (Interleukin 27 Receptor, alpha (IL27RA))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IL27 Receptor alpha antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 纯化方法
- TCCR Antibody is affinity chromatography purified via peptide column.
- 免疫原
- TCCR antibody was raised against a synthetic peptide corresponding to amino acids near the amino terminus of human TCCR precursor. The immunogen is located within the first 50 amino acids of TCCR.
- 亚型
- IgG
- Top Product
- Discover our top product IL27RA Primary Antibody
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- 应用备注
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TCCR antibody can be used for detection of TCCR by Western blot at 1 μ,g/mL. An approximately 70 kDa band can be detected. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- TCCR Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- TCCR antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- IL27 Receptor alpha (IL27RA) (Interleukin 27 Receptor, alpha (IL27RA))
- 别名
- TCCR (IL27RA 产品)
- 别名
- IL27RA antibody, CRL1 antibody, IL-27RA antibody, IL27R antibody, TCCR antibody, WSX1 antibody, zcytor1 antibody, IL-27R antibody, Tccr antibody, WSX-1 antibody, Wsx1 antibody, interleukin 27 receptor subunit alpha antibody, interleukin-27 receptor subunit alpha antibody, interleukin 27 receptor, alpha antibody, IL27RA antibody, LOC484907 antibody, Il27ra antibody
- 背景
- TCCR Antibody: Upon antigen challenge, T-helper cells differentiate into two functional distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-gamma and lymphotoxin-beta that augment cell mediated immune response while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned. It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1. TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-gamma and Th1-dependent antibody IgG2a. TCCR is predominately expressed in thymus, spleen, lymph notes and peripheral blood leukocytes.
- 分子量
- 70 kDa
- 基因ID
- 9466
- NCBI登录号
- NP_004834
- UniProt
- Q6UWB1
- 途径
- Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response
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