IL21 Receptor 抗体 (AA 80-130)
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Quick Overview for IL21 Receptor 抗体 (AA 80-130) (ABIN6990374)
抗原
See all IL21 Receptor (IL21R) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 80-130
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纯化方法
- IL-21 Receptor Antibody is affinity chromatography purified via peptide column.
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免疫原
- IL-21 receptor antibody was raised against a synthetic peptide corresponding to amino acids 97 to 111 of human IL-21 receptor precursor. The immunogen is located within amino acids 80 - 130 of IL-21 Receptor.
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亚型
- IgG
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应用备注
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IL-21 receptor antibody can be used for detection of IL-21 receptor by Western blot at 1-2 μ,g/mL. An approximately 60 kDa band can be detected. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in human and rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- IL-21 Receptor Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- IL-21 Receptor antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
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别名
- IL-21 Receptor
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背景
- IL-21 Receptor Antibody: A novel cytokine related to IL-2 and IL-15 was recently identified and designated IL-21. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor gamma chain, gammac, and mediates IL-21 signaling. Both IL-21R and the gammac are necessary for the IL-21 function. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.
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分子量
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Predicted: 60 kDa
Observed: 62 kDa -
基因ID
- 50615
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NCBI登录号
- NP_068570
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UniProt
- Q9HBE5
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途径
- JAK/STAT Signaling
抗原
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