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IL21 Receptor 抗体 (AA 80-130)

This anti-IL21 Receptor antibody is a 兔 多克隆 antibody detecting IL21 Receptor in WB, ELISA, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6990374
发货至: 中国

Quick Overview for IL21 Receptor 抗体 (AA 80-130) (ABIN6990374)

抗原

See all IL21 Receptor (IL21R) 抗体
IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This IL21 Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 80-130

    纯化方法

    IL-21 Receptor Antibody is affinity chromatography purified via peptide column.

    免疫原

    IL-21 receptor antibody was raised against a synthetic peptide corresponding to amino acids 97 to 111 of human IL-21 receptor precursor. The immunogen is located within amino acids 80 - 130 of IL-21 Receptor.

    亚型

    IgG
  • 应用备注

    IL-21 receptor antibody can be used for detection of IL-21 receptor by Western blot at 1-2 μ,g/mL. An approximately 60 kDa band can be detected. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in human and rat samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    IL-21 Receptor Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    IL-21 Receptor antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

    别名

    IL-21 Receptor

    背景

    IL-21 Receptor Antibody: A novel cytokine related to IL-2 and IL-15 was recently identified and designated IL-21. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor gamma chain, gammac, and mediates IL-21 signaling. Both IL-21R and the gammac are necessary for the IL-21 function. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.

    分子量

    Predicted: 60 kDa

    Observed: 62 kDa        

    基因ID

    50615

    NCBI登录号

    NP_068570

    UniProt

    Q9HBE5

    途径

    JAK/STAT Signaling
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