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IL-21 抗体

The 兔 多克隆 anti-IL-21 antibody (ABIN6990363) specifically detects IL-21 in WB, ELISA 和 ICC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN6990363
发货至: 中国
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Quick Overview for IL-21 抗体 (ABIN6990363)

抗原

See all IL-21 (IL21) 抗体
IL-21 (IL21) (Interleukin 21 (IL21))

适用

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人, 小鼠, 大鼠

宿主

  • 74
  • 26
  • 5
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  • 1

克隆类型

  • 77
  • 27
  • 5
多克隆

标记

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This IL-21 antibody is un-conjugated

应用范围

  • 63
  • 50
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Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
  • 特异性

    At least two isoforms of IL-21 are known to exist, this antibody will detect both isoforms. IL-21 antibody is predicted to not cross-react with other members of the interleukin protein family.

    纯化方法

    IL-21 Antibody is affinity chromatography purified via peptide column.

    免疫原

    Anti-IL-21 antibody was raised against a peptide corresponding to 15 amino acids near the center of human IL-21 precursor. The immunogen is located within the last 50 amino acids of IL-21.

    亚型

    IgG
  • 应用备注

    WB: 1 μ,g/mL, ICC: 2 μ,g/mL.

    Antibody validated: Western Blot in human, mouse and rat samples, Immunocytochemistry in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    IL-21 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    IL-21 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    IL-21 (IL21) (Interleukin 21 (IL21))

    别名

    IL-21

    背景

    IL-21 Antibody: A novel cytokine was recently identified in human and mouse and designated IL-21, which has significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor gamma chain, gammac, and mediates IL-21 signaling. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21 is expressed in activated T cells, and HL-60 and THP-1 cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.

    分子量

    Predicted: 18kD

    Observed: 17 kD kDa

    基因ID

    59067

    NCBI登录号

    NP_068575

    UniProt

    Q9HBE4

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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