IL-21 抗体
Our Local Distributor
北京 101111
Quick Overview for IL-21 抗体 (ABIN6990363)
抗原
See all IL-21 (IL21) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- At least two isoforms of IL-21 are known to exist, this antibody will detect both isoforms. IL-21 antibody is predicted to not cross-react with other members of the interleukin protein family.
-
纯化方法
- IL-21 Antibody is affinity chromatography purified via peptide column.
-
免疫原
- Anti-IL-21 antibody was raised against a peptide corresponding to 15 amino acids near the center of human IL-21 precursor. The immunogen is located within the last 50 amino acids of IL-21.
-
亚型
- IgG
-
-
-
-
应用备注
-
WB: 1 μ,g/mL, ICC: 2 μ,g/mL.
Antibody validated: Western Blot in human, mouse and rat samples, Immunocytochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- IL-21 Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- IL-21 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- IL-21 (IL21) (Interleukin 21 (IL21))
-
别名
- IL-21
-
背景
- IL-21 Antibody: A novel cytokine was recently identified in human and mouse and designated IL-21, which has significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor gamma chain, gammac, and mediates IL-21 signaling. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21 is expressed in activated T cells, and HL-60 and THP-1 cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.
-
分子量
-
Predicted: 18kD
Observed: 17 kD kDa -
基因ID
- 59067
-
NCBI登录号
- NP_068575
-
UniProt
- Q9HBE4
-
途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
-