DC-SIGN/CD209 抗体
Quick Overview for DC-SIGN/CD209 抗体 (ABIN6990355)
抗原
See all DC-SIGN/CD209 (CD209) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
纯化方法
- DC-SIGN Antibody is affinity chromatography purified via peptide column.
-
免疫原
- DC-SIGN antibody was raised against a synthetic peptide corresponding to 21 amino acids near the center of human DC-DIGN. The immunogen is located within the last 50 amino acids of DC-SIGN.
-
亚型
- IgG
-
-
-
-
应用备注
-
DC-SIGN antibody can be used for detection of DC-SIGN by Western blot at 1 to 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- DC-SIGN Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- DC-SIGN antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- DC-SIGN/CD209 (CD209) (CD209)
-
别名
- DC-SIGN
-
背景
- DC-SIGN Antibody: Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes, where DCs hand over HIV to CD4+ T lymphocytes. DCs also amplify the amount of virus and extend the duration of viral infectivity. Multiple strains of HIV-1, HIV-2 and SIV bind to DCs via DC-SIGN. ICAM-3 is the natural ligand for DC-SIGN. A DC-SIGN homologue (termed DC-SIGNR, L-SIGN, and DC-SIGN2) was identified recently. DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR. The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum.
-
分子量
-
Predicted: 44 kDa
Observed: 47 kDa -
基因ID
- 30835
-
UniProt
- Q9NNX6
抗原
-