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PD-L1 抗体 (Isoform 1)

Name: PD-L1 抗体 (Isoform 1)
Brand: antibodies-online
SKU: ABIN6990335
Availability: OutOfStock

This anti-PD-L1 antibody is a 兔多克隆 antibody detecting PD-L1 in WB, FACS, ELISA, IF 和 IHC (p). Suitable for 人, 小鼠和大鼠.

产品编号 ABIN6990335

发货至: 中国

Quick Overview for PD-L1 抗体 (Isoform 1) (ABIN6990335)

抗原

See all PD-L1 抗体

PD-L1 (CD274 (PD-L1))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This PD-L1 antibody is un-conjugated

应用范围

Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product PD-L1 Primary Antibody

抗原表位
31

29

16

15

10

9

7

7

7

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4

4

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
AA 60-110, Isoform 1

特异性

PD-L1 antibody has no cross-reactivity to PD-L2.

纯化方法

PD-L1 Antibody is affinity chromatography purified via peptide column.

免疫原

Anti-PD-L1 antibody was raised against a peptide corresponding to 17 amino acids near the center of human PD-L1 isoform 1. The immunogen is located within amino acids 60 - 110 of PD-L1.

亚型

IgG
anti-CD274 (PD-L1) (C-Term) antibody
Verified PD-L1 适用: 人 WB, FACS, ELISA, IF 宿主: 山羊 Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 19-238) antibody
PD-L1 适用: 人 WB, FACS, IHC, ELISA, IF 宿主: 小鼠 Monoclonal 9B5F4 unconjugated

anti-CD274 (PD-L1) (AA 39-191) antibody
PD-L1 适用: 人, 小鼠 WB, FACS, IHC, ELISA, IF, Coat, StM 宿主: 小鼠 Monoclonal PDL1-2746 unconjugated

anti-CD274 (PD-L1) (AA 24-153) antibody
PD-L1 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 6D9A2 unconjugated

anti-CD274 (PD-L1) (AA 48-290) antibody
PD-L1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 34-241) antibody
PD-L1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 19-238) antibody
PD-L1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-CD274 (PD-L1) (C-Term) antibody
KO Validated PD-L1 适用: 人 WB, FACS, IF, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 24-153) antibody
PD-L1 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 7D2A10 unconjugated

anti-CD274 (PD-L1) (AA 24-234) antibody
PD-L1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1-2 μ,g/mL, IHC-P: 2.5-5 μ,g/mL, IF: 20 μ,g/mL, Flow Cyt: 0.5 μ,g/mL.

Antibody validated: Western Blot in human and mouse samples, Immunohistochemistry in human and rat samples, Immunofluorescence in human and rat samples and Flow Cytometry in mouse samples. All other applications and species not yet tested.

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

PD-L1 Antibody is supplied in PBS containing 0.02 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C,4 °C

储存方法

PD-L1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
抗原

PD-L1 (CD274 (PD-L1))

别名

PD-L1

背景

PD-L1 plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/CD279, PD-L1 modulates the activation threshold of T-cells and limits T-cell effector response (1). The PDCD1/CD279-mediated inhibitory pathway is exploited by tumors to attenuate anti-tumor immunity and facilitate tumor survival (2,3). Through a yet unknown activating receptor, it may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10) (4).

分子量

Predicted: 33 kDa

Observed: 37 kDa

基因ID

29126

NCBI登录号

NP_054862

UniProt

Q9NZQ7

途径

Cancer Immune Checkpoints